이하선부에 발생한 Kimura’s disease에 대한 치험례
A case report of Kimura’s disease in the parotid region
변성수, 김형준, 차인호, 김현실, 정휘동, 최영달,
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변성수 ( Byun Sung-Soo ) - 연세대학교 치과대학 구강악안면외과학교실
김형준 ( Kim Hyung-Jun ) - 연세대학교 치과대학 구강악안면외과학교실
차인호 ( Cha In-Ho ) - 연세대학교 치과대학 구강악안면외과학교실
김현실 ( Kim Hyun-Sil ) - 연세대학교 치과대학 구강병리학교실
정휘동 ( Jung Hwui-Dong ) - 연세대학교 치과대학 구강악안면외과학교실
최영달 ( Choi Young-Dal ) - 연세대학교 치과대학 구강악안면외과학교실
KMID : 0355620070330050554
Abstract
Kimura’s disease is a chronic inflammatory disorder presenting regional lymphadenopathy with painless soft tissue mass. Clinically, peripheral eosinophilia and elevated serum IgE levels are observed, and proteinuria associated with renal disease can also be present. Although its etiology is not clearly understood, it occurs predominantly in young Asian males and presents as a deep, subcutaneous mass involving salivary glands of the preauricular and submandibular regions. Spontaneous remission is very rare, and although treatments such as steroid, cytotoxic therapy and irradiation are available, chronic recurrence is very common. As such, surgical excision is regarded as the mainstay of therapy for localized lesions. Histopathologically, Kimura’s disease features eosinophilic abscsesses and dense lymphoid aggregates with germinal center. Clinical differential diagnosis of Kimura’s disease from other parotid diseases with accompanying lymphadenopathy is often very challenging prior to biopsy. The authors report a case of a 19-year-old male diagnosed with Kimura’s disease in the parotid region who underwent surgical excision and was followed up for 6 years, along with a review of related literature
키워드
Kimura disease;Eosinophilia;Lymphadenopathy;IgE;Angiolymphoid hyperplasia with eosinophilia
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